Sign up for Equitymaster's free daily newsletter, The 5 Minute WrapUp and get access to our latest Multibagger guide (2017 Edition) on picking money-making stocks.

This is an entirely free service. No payments are to be made.

Download Now Subscribe to our free daily e-letter, The 5 Minute WrapUp and get this complimentary report.
We hate spam as much as you do. Check out our Privacy Policy and Terms Of Use.
Bioinformatics: An introduction - Views on News from Equitymaster
  • E-MAIL
  • A  A  A
  • Jun 28, 2001

    Bioinformatics: An introduction

    Bioinformatics is the new mantra thatís invading and converging two new economy sectors, pharmaceuticals and IT. Bioinformatics is the field of biotechnology that allows the study of genes and proteins using computers and other forms of technology. It involves creating databases of genomes and protein sequences. It also involves methods to build 3-D models of proteins, which can show potential binding sites for drugs. The purpose of bioinformatics is to eventually be able to use technology to predict information about genes, given only its primary DNA sequence.

    Bioinformatics processes include homology searches, structure, function prediction, domain analysis, and Single Nucleotide Polymorphism (SNP) mapping. Homology searching is a process where you can compare DNA or protein sequence to all sequences known. This whole process is run through software, and hence forms a basis of bioinformatics. As scientists discover more and more sequences, the database search becomes increasingly complex. A good database search can either identify your sequence or predict the function of your sequence by finding a similar sequence. Genes and proteins come in families. This known fact makes the process of sequence identification simpler. One method that assists in SNP changes may or may not cause noticeable changes in the DNA structure. However, even SNPís that do not cause a defect can still be useful, because they are often located very close to a mutation. If the SNP is repeatedly found located next to a mutation, then the identification of a SNP can serve as a diagnostic for a defect gene. In addition, studying shifts in SNPís between individuals can give scientists clues to the origin of humans and the link between different races.

    SNPís can be identified using high throughput screening (HTS) and parallel analysis. HTS shows which compounds are insensitive to protein sequence variation. It allows for the stratification of patient populations by screening patient response to drug metabolism. This is used to reduce random side effects.

    The market for bioinformatics - based services and databases is expected to well surpass US$ 2 bn in a couple of years, though a large part of the global bioinformatics market is centered around the US. India was amongst the first to coin the biotechnology word, with department of biotechnology setting up 9 distributed information centers way back in 1988. With strengths in mathematics, computing, physics and chemistry and above all low cost high quality IT, the country is well positioned ideally to emerge as a frontrunner in varied opportunities that bioinformatics offer.



    Equitymaster requests your view! Post a comment on "Bioinformatics: An introduction". Click here!


    Copyright © Equitymaster Agora Research Private Limited. All rights reserved.
    Any act of copying, reproducing or distributing this newsletter whether wholly or in part, for any purpose without the permission of Equitymaster is strictly prohibited and shall be deemed to be copyright infringement.

    LEGAL DISCLAIMER: Equitymaster Agora Research Private Limited (hereinafter referred as 'Equitymaster') is an independent equity research Company. Equitymaster is not an Investment Adviser. Information herein should be regarded as a resource only and should be used at one's own risk. This is not an offer to sell or solicitation to buy any securities and Equitymaster will not be liable for any losses incurred or investment(s) made or decisions taken/or not taken based on the information provided herein. Information contained herein does not constitute investment advice or a personal recommendation or take into account the particular investment objectives, financial situations, or needs of individual subscribers. Before acting on any recommendation, subscribers should consider whether it is suitable for their particular circumstances and, if necessary, seek an independent professional advice. This is not directed for access or use by anyone in a country, especially, USA or Canada, where such use or access is unlawful or which may subject Equitymaster or its affiliates to any registration or licensing requirement. All content and information is provided on an 'As Is' basis by Equitymaster. Information herein is believed to be reliable but Equitymaster does not warrant its completeness or accuracy and expressly disclaims all warranties and conditions of any kind, whether express or implied. Equitymaster may hold shares in the company/ies discussed herein. As a condition to accessing Equitymaster content and website, you agree to our Terms and Conditions of Use, available here. The performance data quoted represents past performance and does not guarantee future results.

    SEBI (Research Analysts) Regulations 2014, Registration No. INH000000537.

    Equitymaster Agora Research Private Limited. 103, Regent Chambers, Above Status Restaurant, Nariman Point, Mumbai - 400 021. India.
    Telephone: +91-22-61434055. Fax: +91-22-22028550. Email: info@equitymaster.com. Website: www.equitymaster.com. CIN:U74999MH2007PTC175407

    Become A Smarter Investor In
    Just 5 Minutes

    Multibagger Stocks Guide 2017
    Get our special report, Multibagger Stocks Guide (2017 Edition) Now!
    We will never sell or rent your email id.
    Please read our Terms